Xanthogranulomatous pyelonephritis: King Faisal Specialist Hospital experience

Clinicopathologic features in a series of 11 cases of xanthogranulomatous pyelonephritis are reviewed. There were seven males and four females ranging in age from 6-56 years with an average age of 34 years. The disease was unilateral in ten cases and bilateral in one. There was associated urinary tract obstruction in eight cases due to renal or ureteric stones (5), ureteric stricture (2), and carcinoma of the urinary bladder (1). Two of the patients were renal transplant recipients in which native kidneys were involved by xanthogranulomatous pyelonephritis. In one of these cases, a small renal cell carcinoma was found in one kidney along with amyloidosis involving both kidneys. Radiologic findings were mostly non-specific. These findings are briefly discussed in light of the salient features of this disease as published in the literature.