Related Experiment Video
Updated: Jul 14, 2026

Assessment of Intestinal Transcytosis of Neonatal Escherichia coli Bacteremia Isolates
Published on: February 17, 2023
Campylobacter jejuni enterocolitis in neonates
A H Rashid1, H Salman, M I Hussain
1Department of Pediatrics, Suleimania Children's Hospital, Riyadh, Saudi Arabia.
Insights
Campylobacter jejuni causes gastroenteritis in children. This study details six cases of neonatal enterocolitis from Campylobacter in Saudi Arabia, highlighting key symptoms like diarrhea, fever, and bloody stools.
Area of Science:
- Pediatrics
- Infectious Diseases
- Microbiology
Background:
- Campylobacter jejuni is a major cause of childhood gastroenteritis.
- Neonatal enterocolitis due to Campylobacter is rarely documented globally.
- No prior cases were reported in Saudi Arabia.
Purpose of the Study:
- To report the first cases of neonatal enterocolitis caused by Campylobacter jejuni in Saudi Arabia.
- To describe the clinical presentation and management of these cases.
Main Methods:
- Retrospective case series analysis.
- Inclusion of six neonates diagnosed with Campylobacter enterocolitis between September 1989 and January 1991.
- Review of patient records for symptoms, stool characteristics, and treatment.
Main Results:
- Six neonates presented with diarrhea (1-20 days duration).
- Three neonates had bloody stools, and two had mucus.
- Five neonates exhibited fever, a finding contrasting with previous literature.
- Various antibiotic treatments were administered, including erythromycin and augmentin.
Conclusions:
- Campylobacter infection should be considered in neonates with diarrhea, especially when accompanied by mucus and blood.
- Fever may be a more common presenting symptom in neonates than previously reported.
Abstract:
Campylobacter jejuni is one of the leading bacterial pathogens causing acute gastroenteritis in children. Only a few cases have been described in the world literature about neonatal enterocolitis due to campylobacter and none from Saudi Arabia. We describe six cases of neonatal enterocolitis due to this organism isolated during the period from September 1989 - January 1991 at Suleimania Children's Hospital, Riyadh, Saudi Arabia. All of the patients presented with diarrhea; duration ranging from 1-20 days. Three patients had blood and two had mucus in their stool. In contrast to the findings of other investigators, five neonates presented with fever. One neonate was treated with erythromycin, another received augmentin, and two received other antibiotics because of suspected sepsis. In one patient, previous antibiotics were discontinued and erythromycin was added and two received no antibiotics. Campylobacter infection should be suspected in any neonate presenting with diarrhea accompanied by mucus and blood in the stool.
More Related Videos
Related Concept Videos
Bacterial Gastroenteritis
Botulism
Bacterial Meningitis I: Introduction
Stringent Response in E. coli
Bacterial Meningitis II: Pathophysiology
Bacterial Meningitis

