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Updated: Oct 14, 2026

PLGA Nanoparticles Formed by Single- or Double-emulsion with Vitamin E-TPGS
Published on: December 27, 2013
[Parameters for the formulation of physical-technical characteristics of granules of theophylline obtained by
B Bataille1, L Rahman, M Jacob
1Laboratoire de Pharmacie Galénique, Pharmacotechnie et Biopharmacie, Faculté de Pharmacie Université de Montpellier 1.
Abstract:
Spheroids are prepared from microcrystalline cellulose in binary and compound combination with lactose and theophylline, in certain fixed conditions of extrusion and of spheronisation. The present work envisages the influence of combinated raw materials upon the physical-technique characteristic of the made spheroids. Besides a variation in the granulometric distribution a statical study through analysis of variance brings to the fore that the parameters of formulation contribute to modify the properties of hardness and of friability of the minigranules.
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