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Updated: Jul 14, 2026
A Reversible Silicon Oil-Induced Ocular Hypertension Model in Mice
Published on: November 15, 2019
[Optical coherence tomography macular study on eyes filled with silicone oil]
Otacílio de Oliveira Maia1, Walter Yukihiko Takahashi, Yoshitaka Nakashima
1Departamento de Oftalmologia, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil. omaiausp@uol.com.br
Purpose:
To demonstrate optical coherence tomography efficacy to evaluate macular anatomical outcomes, in eyes with silicone oil-filled vitreous cavity after vitrectomy.
Methods:
A descriptive observational study of 28 (twenty-eight) patients submitted to pars plana vitrectomy having silicone oil as vitreous substitute. The macular findings were observed by means of indirect binocular ophthalmoscope, biomicroscopy and optical coherence tomography examinations.
Results:
During the follow-up period the retina remained attached in all patients. In some cases, intraretinal cysts, epiretinal membrane and lamellar macular hole were observed only by optical coherence tomography examination.
Conclusion:
Optical coherence tomography provided improved imaging of finer retinal structures in eyes with silicone oil-filled vitreous cavity. Therefore, optical coherence tomography examination should be systematically performed in eyes filled with silicone oil to recognize changes in retinal morphology.
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