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Updated: Jul 14, 2026

Induction of Experimental Autoimmune Encephalomyelitis in Mice and Evaluation of the Disease-dependent Distribution of Immune Cells in Various Tissues
Published on: May 8, 2016
[The role of chemokines in uveitis]
Roberto Martins Gonçalves1, Antônio Lúcio Teixeira, Wesley Ribeiro Campos
1Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brasil. robertomgoncalves@gmail.com
Abstract:
Inflammation is part of the physiological process that aims at repairing the damage produced by different causes such as infection, trauma, and autoimmune disease. However, when this physiological process is not regulated, it can contribute to the increase in tissue damage. Chemokines and their receptors are major factors involved in the process of cell migration into inflamed tissues. In the ocular diseases, mainly in uveitis, such proteins have been identified as important mediators of the inflammation process. This review discusses the role of chemokines in several ocular diseases, with emphasis on the uveitic process.
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