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Gastroesophageal reflux in patients with recurrent laryngeal papillomatosis

Shirley Shizue Nagata Pignatari1, Raquel Ysabel Guzmán Liriano, Melissa A G Avelino

  • 1Dept. Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, Escola Paulista de Medicina, Universidade Federal de São Paulo. pigna@terra.com.br

Brazilian Journal of Otorhinolaryngology
|June 26, 2007
PubMed

Insights

Gastroesophageal reflux is common in children with recurrent laryngeal papillomatosis. High rates of proximal reflux suggest a link between reflux and this condition, impacting its severity.

Area of Science:

  • Pediatric Otolaryngology
  • Gastroenterology
  • Respiratory Medicine

Background:

  • Gastroesophageal reflux (GER) is increasingly linked to pediatric respiratory disorders.
  • Conditions like stridor, chronic cough, pneumonia, and bronchitis may stem from GER.
  • GER might also influence the recurrence and severity of recurrent laryngeal papillomatosis (RLP).

Purpose of the Study:

  • To investigate the frequency and intensity of GER in children diagnosed with RLP.

Main Methods:

  • A study involving ten pediatric patients (ages 3-12) with RLP.
  • Utilized 24-hour double-probe pH-metry to assess GER.

Main Results:

  • Fifty percent of RLP patients showed distal sphincter GER.
  • A significant 90% of RLP patients exhibited proximal sphincter GER.

Conclusions:

  • The incidence of proximal GER is markedly elevated in children with RLP.
  • This finding suggests a strong association between proximal GER and RLP.
Abstract

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