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Updated: Jul 14, 2026
14:39
Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
Evidence-based pharmacologic treatment for mild asthma
1Department of Respiratory and Sleep Medicine, Royal Melbourne Hospital, Melbourne, Vic., Australia. kohsiyue@yahoo.com.sg
International Journal of Clinical Practice
|June 26, 2007
Summary
Inhaled corticosteroids (ICS) are the primary treatment for mild persistent asthma, offering better control and lung function improvement than other therapies. Early ICS intervention reduces severe exacerbations in new-onset mild asthma.
Area of Science:
- Pulmonology
- Allergy and Immunology
- Pharmacology
Background:
- Mild asthmatics represent the majority of asthma patients.
- There is a lack of evidence-based treatment guidelines for mild asthma compared to severe asthma.
Purpose of the Study:
- To conduct an up-to-date literature review on asthma therapy for mild persistent asthma patients.
- To identify potential clinical trials for mild asthma treatment.
Main Methods:
- Literature search of MEDLINE (1965-2007) and Cochrane library (up to February 2007).
Main Results:
- Inhaled corticosteroids (ICS) are the cornerstone of treatment for mild persistent asthma.
- Early ICS intervention reduces severe exacerbations and improves asthma control in recent-onset mild asthma.
- ICS demonstrate superiority over leukotriene receptor antagonists and xanthines for asthma control and lung function.
Conclusions:
- ICS are the preferred treatment for mild persistent asthma.
- Consider adding long-acting beta2-agonists for moderately persistent or poorly controlled asthma on low-dose ICS.
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