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Hemocompatibility Testing of Blood-Contacting Implants in a Flow Loop Model Mimicking Human Blood Flow
Published on: March 5, 2020
[Study on biocompatibility of MIM 316L stainless steel]
Guohui Wang1, Shaihong Zhu, Yiming Li
1Transplantation Medical Academy, Third XiangYa Hospital, Central South University, Changsha 410013, China.
Abstract:
This study was aimed to evaluate the biocompatibility of metal powder injection molding (MIM) 316L stainless steel. The percentage of S-period cells was detected by flow cytometry after L929 cells being incubated with extraction of MIM 316L stainless steel, and titanium implant materials for clinical application were used as control. In addition, both materials were implanted in animals and the histopathological evaluations were carried out. The statistical analyses show that there are no significant differences between the two groups (P > 0.05), which demonstrate that MIM 316L stainless steel has good biocompatibility.

