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Updated: Jul 14, 2026

Quantitative Analysis of Viscoelastic Properties of Red Blood Cells Using Optical Tweezers and Defocusing Microscopy
Published on: March 25, 2022
[Study of Raman spectroscopy of optically trapped human red blood cell affected by direct current]
Liangyue Yue1, Guiwen Wang, Ling Fang
1Physical Department of Guangxi Medical University, Nanning 530021, China.
Abstract:
Laser tweezers Raman spectroscopy (LTRS) system is a combination of spectroscopy and laser tweezers; It is a new method of studying cells; It can trap single living cell and make Raman spectrum of single living cell. From the positions, intensities, and line widths of the Raman peaks in the spectra, we can get useful information about composition, structure and interactions of complexes inside the living cells. External agents may change cell's physiological state and this changed information can also be got from Raman spectra. This article is a study of Raman spectra of human red blood cell (RBC) affected by different intensity direct current (DC); from the result, distinct change of Raman spectra of RBC have been got. These changes characterize the changes of the internal information of the cells. This article give some academic reference of physical therapy using DC in the level of molecule.
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