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Update on lymphogranuloma venereum in the United Kingdom
Heather Jebbari1, Sarah Alexander, Helen Ward
1Health Protection Agency, Centre for Infections, London, UK. catherine.ison@hpa.org.uk.
Sexually Transmitted Infections
|June 27, 2007
Summary
The UK epidemic of lymphogranuloma venereum (LGV) continues, primarily affecting white men who have sex with men (MSM). High rates of HIV co-infection persist, with a recent decline in cases possibly linked to fewer sexual contacts.
Area of Science:
- Public Health
- Epidemiology
- Infectious Diseases
Background:
- Lymphogranuloma venereum (LGV) is a sexually transmitted infection caused by specific serovars of Chlamydia trachomatis.
- An outbreak of LGV primarily affecting men who have sex with men (MSM) has been ongoing in the UK.
Purpose of the Study:
- To provide an update on the epidemiology of LGV in the United Kingdom up to April 2007.
- To describe the demographic characteristics and co-infection rates of diagnosed LGV cases.
Main Methods:
- Enhanced surveillance data and laboratory reports were analyzed.
- Data collection covered the period from October 2004 to April 2007.
Main Results:
- 492 cases of LGV were diagnosed between October 2004 and April 2007.
- The majority of cases (99%) were among MSM, predominantly white, with a median age of 40.
- High rates of co-infection were observed, including HIV (74%), hepatitis C (14%), and syphilis (5%).
Conclusions:
- The LGV epidemic in the UK continues, with consistent demographic profiles and high HIV co-infection rates.
- A decrease in reported sexual contacts may be contributing to the observed decline in cases, though LGV may also be shifting within risk groups.
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