Water and deuterium oxide permeability through aquaporin 1: MD predictions and experimental verification

Artem B Mamonov1, Rob D Coalson, Mark L Zeidel

  • 1Department of Chemistry, University of Pittsburgh, Pittsburgh, PA 15260, USA.

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Reabsorption and Secretion in the DCT and Collecting Duct

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The distal part of the DCT, along with the...
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¹H NMR of Labile Protons: Deuterium (²H) Substitution

This lesson illustrates the role of deuterium substitution in simplifying the NMR spectrum of compounds comprising labile protons. One method employed is the use of deuterium. Amongst the three isotopes of hydrogen, deuterium (2H) has a nucleus composed of one proton and one neutron. When the D2O solvent is added to a pure dry ethanol solution, its labile proton is substituted with deuterium.
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Water, like other substances, moves from a high concentration of free water...
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