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Related Experiment Videos

Reducing ventricular pacing in sinus node dysfunction.

Toshiyuki Ishikawa1, Shinichi Sumita, Masami Kosuge

  • 1Second Department of Internal Medicine, Yokohama City University Hospital, Yokohama.

International Heart Journal
|June 27, 2007
PubMed
Summary
This summary is machine-generated.

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Dual-chamber pacing in DDIR mode significantly reduced ventricular pacing and atrial tachyarrhythmias compared to DDDR mode with mode switch in patients with intact AV conduction. This suggests DDIR mode offers benefits for device longevity and programming simplicity.

Area of Science:

  • Cardiology
  • Biomedical Engineering
  • Electrophysiology

Background:

  • Dual-chamber pacing modes (DDIR and DDDR) are used for bradycardia management.
  • DDDR mode with mode switch is standard for AV block, but DDIR may benefit patients with intact AV conduction.
  • Limited data exists comparing DDIR and DDDR with mode switch regarding ventricular pacing and atrial tachyarrhythmias.

Purpose of the Study:

  • To compare the incidence of ventricular pacing and atrial tachyarrhythmia between DDIR and DDDR modes with mode switch.
  • To evaluate the clinical utility of DDIR versus DDDR with mode switch in patients with intact AV conduction.

Main Methods:

  • Randomized, single-blind, crossover study design.
  • Twenty-four patients with bradycardia-tachycardia syndrome and intact AV conduction were enrolled.

Related Experiment Videos

  • Patients were randomized to DDIR or DDDR modes for 12 weeks, then switched to the opposite mode.

    • Main Results:

    • Significantly less ventricular pacing was observed in DDIR mode (48.9%) compared to DDDR mode (76.5%) (P = 0.0002).
    • Atrial high-rate episodes were significantly lower in DDIR mode (1.32 per day) versus DDDR mode (1.85 per day) (P < 0.05).

    Conclusions:

    • DDIR mode may be beneficial for patients with sinus node dysfunction and intact AV conduction.
    • DDIR mode can simplify device programming and potentially improve device longevity.
    • DDIR mode may help in avoiding atrial tachyarrhythmias.