Intraocular lacrimal gland choristoma diagnosed by fine-needle aspiration biopsy
Elie G Kobrin1, Carol L Shields, Carl J Danzig
1Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Insights
A rare intraocular lacrimal gland choristoma was diagnosed in a child using fine-needle aspiration biopsy. This case highlights the diagnostic utility of fine-needle aspiration biopsy for this condition.
Area of Science:
- Ophthalmology
- Pediatric Ophthalmology
- Oncology
Background:
- Intraocular lacrimal gland choristoma is a rare congenital tumor.
- Accurate diagnosis is crucial for appropriate management in pediatric patients.
Observation:
- A 6-year-old girl presented with a pink, vascularized, cerebriform mass on the iris with significant corectopia.
- Differential diagnoses included various ocular tumors and malformations.
- Fluorescein angiography indicated a solid, noninflammatory mass.
Findings:
- Fine-needle aspiration biopsy revealed benign epithelial cells.
- Histological findings were consistent with lacrimal gland choristoma.
Implications:
- Fine-needle aspiration biopsy is a valuable tool for confirming intraocular lacrimal gland choristoma.
- Early diagnosis and characterization are essential for pediatric ocular oncology.
Purpose:
To describe an intraocular lacrimal gland choristoma confirmed with fine-needle aspiration biopsy in a child.
Methods:
Case report.
Results:
A 6-year-old Asian girl developed a pink, vascularized, cerebriform mass with marked corectopia in the inferonasal iris of the left eye. The differential diagnosis included juvenile xanthogranuloma, nevus, melanoma, medulloepithelioma, lacrimal gland choristoma, and atypical retinoblastoma. Fluorescein angiography was suggestive of a noninflammatory, nonleaking solid mass. Fine-needle aspiration biopsy showed benign epithelial cells consistent with lacrimal tissue.
Conclusion:
Lacrimal gland choristoma shows notable clinical features and fine-needle aspiration biopsy can be confirmatory.


