Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Calculating percent depth dose with the electron pencil-beam redefinition algorithm.

Michael J Price1, Kenneth R Hogstrom, John A Antolak

  • 1Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77070, USA. mjprice@mdanderson.org

Journal of Applied Clinical Medical Physics
|June 27, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Vaccination against tumour endothelial marker Robo4 inhibits tumour growth.

Immunotherapy advances·2026
Same author

"Dirty Fat Pad" Sign: A novel computed tomography (CT) indicator of injury to the posterior ligamentous complex in acute fractures of the thoracolumbar spine.

Injury·2026
Same author

Impact of tumor motion on target delineation and dose calculation accuracy using rapid-acquisition HyperSight CBCT in online adaptive radiotherapy.

Journal of applied clinical medical physics·2025
Same author

Real-time electron spectrometer utilizing a permanent magnet and diode detector array.

Medical physics·2025
Same author

Mini-lattice radiation therapy: A treatment planning approach to miniaturize spatially fractionated lattice radiation therapy using a clinical linear accelerator.

Medical physics·2025
Same author

'Immune reset plus': the case for combining immunotherapies to maintain self-tolerance in autoimmune diseases.

Frontiers in immunology·2025

This study improved the accuracy of the electron pencil-beam redefinition algorithm (PBRA) for calculating radiation doses in water. Method 1 offers a more accurate and simpler approach for clinical use.

Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Dosimetry

Background:

  • Accurate calculation of central-axis percent depth dose (PDD) in water is crucial for radiotherapy planning.
  • The electron pencil-beam redefinition algorithm (PBRA) is used for dose calculations, but its accuracy for rectangular fields requires investigation.

Purpose of the Study:

  • To evaluate and improve the accuracy of the PBRA for calculating central-axis PDD in water for rectangular electron fields.
  • To test the hypothesis that a modified PBRA can achieve 2% or 1-mm accuracy for field sizes >= 2x2 cm at 100-cm source-to-surface distance (SSD).

Main Methods:

  • Investigated two methods (Method 1 and Method 2) for determining the PBRA energy correction factor C(E).
  • Method 1 involved fitting PBRA calculations to individual rectangular-field PDDs using polynomial functions of energy.

Related Experiment Videos

  • Method 2 used a polynomial function of energy and field size C(E,W) for square fields, with rectangular fields derived using the square root method.

    • Main Results:

    • Preliminary investigations showed that a single C(E) was insufficient for accurate PDD calculations.
    • Both Method 1 and Method 2, with modifications to the photon depth dose model, enabled the PBRA to predict PDD within established criteria for all square and rectangular fields.
    • Method 1 demonstrated higher accuracy (within ~1%) and was simpler to implement than Method 2.

    Conclusions:

    • The PBRA, when appropriately calibrated using Method 1, can accurately calculate central-axis PDD in water for rectangular electron fields.
    • Method 1 is recommended for clinical implementation due to its superior accuracy and implementation simplicity.
    • The study confirms the feasibility of achieving high accuracy in electron beam dose calculations for radiotherapy.