Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Interferon in sheep].

M Büttner1, K Wertz, W Hollwich

  • 1Institut für Medizinische Mikrobiologie, Infektions- und Seuchenmedizin der Tierärztlichen Fakultät, Ludwig-Maximilians-Universität München.

Tierarztliche Praxis
|October 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Publicly Available Dental Image Datasets for Artificial Intelligence.

Journal of dental research·2024
Same author

Artificial Intelligence in Orthodontics: Critical Review.

Journal of dental research·2024
Same author

Multi-modal deep learning for automated assembly of periapical radiographs.

Journal of dentistry·2023
Same author

Microbial contamination on ambulance surfaces: a systematic literature review.

The Journal of hospital infection·2022
Same author

Benchmarking atlas-level data integration in single-cell genomics.

Nature methods·2021
Same author

scCODA is a Bayesian model for compositional single-cell data analysis.

Nature communications·2021
Same journal

[Acute glycoside intoxication from the intake of oleander (Nerium oleander) leaves in a guinea pig].

Tierarztliche Praxis·1997
Same journal

[Importance of cytogenetic investigations in canine leukemias].

Tierarztliche Praxis·1997
Same journal

[Imported parasites in dogs: Dirofilaria repens and Dipetalonema reconditum].

Tierarztliche Praxis·1997
Same journal

[Excision arthroplasty of the hip joint in dogs and cats. Clinical, radiographic and gait analysis findings at the surgical veterinary clinic of the Ludwig Maximilians University of Munich].

Tierarztliche Praxis·1997
Same journal

[Excision arthroplasty of the hip joint in dogs and cats. Long-term results of the veterinary surgery clinic at the Justus Liebig University of Giessen].

Tierarztliche Praxis·1997
Same journal

[Scanning electron microscopic investigations on the anatomy of the fetlock joint in horses].

Tierarztliche Praxis·1997
See all related articles

Sheep pregnancy involves ovine trophoblast protein-1 (oTP-1) signaling, while lentivirus-induced interferon (LV-IFN) contributes to Maedi/Visna pathogenesis. Ovine interferon gamma (IFN gamma) induction was also characterized.

Area of Science:

  • Immunology
  • Reproductive Biology
  • Veterinary Virology

Background:

  • Limited information exists on sheep interferon (IFN) subtypes and their roles.
  • Recent research has identified key IFNs involved in sheep reproduction and disease.

Purpose of the Study:

  • To summarize recent findings on ovine interferon (IFN) alpha, ovine trophoblast protein-1 (oTP-1), lentivirus-induced interferon (LV-IFN), and ovine interferon gamma (IFN gamma).
  • To elucidate the roles of these IFNs in sheep pregnancy and disease pathogenesis.

Main Methods:

  • Characterization of oTP-1 secreted by fetal trophectoderm during early gestation.
  • Investigation of LV-IFN's role in the pathogenesis of Maedi/Visna.
  • Analysis of mitogen- or antigen-dependent induction and characterization of ovine IFN gamma.

Related Experiment Videos

Main Results:

  • oTP-1 is crucial for pregnancy signaling in ewes, potentially by influencing prostaglandin metabolism.
  • LV-IFN appears to limit viral replication, contributing to virus persistence and chronic inflammation in Maedi/Visna.
  • Ovine IFN gamma induction and characteristics have been described.

Conclusions:

  • Sheep interferons, including oTP-1, LV-IFN, and IFN gamma, play significant roles in reproductive signaling and disease processes.
  • Further research into ovine IFNs can advance understanding of sheep health and productivity.