Related Experiment Video
Updated: Jul 14, 2026

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging
Published on: September 12, 2011
Neurobiology of autism: neuropathology and neuroimaging studies
B Payá González1, N Fuentes Menchaca
1Programa de Salud Mental Infanto-Juvenil, C. H. Padre Menni, Santander, Spain. hdtca@mennisant.com
Introduction:
This study performs a review of the last studies in the field of neuropathology and neuroimaging of autism.
Method:
A search was done in Medline for articles on neuropathology and neuroimaging in autism and the most relevant articles of the last 10 years up to date were selected.
Results:
The existence of structural abnormalities in the brain of patients with autism, affecting different brain structures such as the cerebellum, limbic system, frontal and temporal cortexes, corpus callosum and basal ganglia seems to be demonstrated.
Conclusion:
The alterations found with the neuroimaging techniques are identified in the different brain structures. At present, there is almost generalized thinking that brain alterations in autism are not limited to a single brain area but involve different structures within a globally affected neuronal network. Future studies will allow us to increase knowledge on this disorder's pathophysiology.
Related Concept Videos
Autism Spectrum Disorder
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
Alzheimer Disease ll: Pathophysiology
Biological Causes of Schizophrenia
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin studies.
Brain Imaging
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within the...
Introduction to Biological Bases of Psychology
The nervous system, the cornerstone of...

