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Updated: Jul 14, 2026

Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade
Published on: August 14, 2019
Role of flavonoids and vitamins in cancer
Maria Luisa Castellani1, Yazdani B Shaik, Lakshmi Narayan Shanmugham
1Department of Medicine and Aging, Medical School, University of Chieti-Pescara, Via dei Vestini, Chieti, Italy.
Abstract:
Flavonoids are naturally occurring polyphenolic plant compounds that are capable of inhibiting histamine and cytokine release from several cells. Many studies suggest that flavonoids are anticancer agents with an apoptotic effect on tumor cells. Studies with animal tumour models have found vitamin deficiency to enhance susceptibility to chemical carcinogenesis and large doses of anti-oxidant vitamins and flavonoids to inhibit carcinogenesis. In some studies flavonoids and/or vitamins were found to reduce the predisposition to develop tumours in animals and humans. In conclusion, in this review we describe the role of flavonoids and vitamins in cancer.
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