Related Experiment Video
Updated: Jul 14, 2026

Inhibition of Aspergillus flavus Growth and Aflatoxin Production in Transgenic Maize Expressing the α-amylase Inhibitor from Lablab purpureus L.
Published on: February 15, 2019
Harmful fungi in both agriculture and medicine
1Southern Regional Research Center, USDA, ARS, New Orleans, LA 70124, USA. adelucca@srrc.ars.usda.gov
Abstract:
Most fungi are saprophytic and not pathogenic to plants, animals and humans. However, a relative few fungal species are phytopathogenic, cause disease (e.g., infections, allergies) in man, and produce toxins that affect plants, animals and humans. Among such fungi are members of the Aspergillus and Fusarium genera as well as other genera (e.g., Alternaria, Mucor) comprising the emerging pathogen group in humans. These fungi present a common threat to both agricultural production and the health of healthy and immunocompromised individuals. Taken together, these relative few fungi can cause huge economic losses to agriculture, loss of food for consumption, and serious, often fatal diseases in humans and animals. Plants may be a source of antifungal compounds since they have had to develop compounds to resist infections by fungi present in their environment.
Insights
Certain fungi pose significant threats to agriculture and health, causing crop losses and serious diseases in humans and animals. Plants may offer a natural source of antifungal compounds to combat these emerging pathogens.
Area of Science:
- Mycology
- Plant Pathology
- Medical Mycology
Background:
- Most fungi are saprophytic, playing essential roles in ecosystems.
- A small subset of fungi are pathogenic to plants, animals, and humans.
- Genera like Aspergillus, Fusarium, Alternaria, and Mucor represent emerging fungal pathogens.
Purpose of the Study:
- To highlight the dual threat of pathogenic fungi to agriculture and human/animal health.
- To underscore the economic impact of fungal diseases in agriculture and food security.
- To explore the potential of plants as a source for novel antifungal compounds.
Main Methods:
- Literature review and synthesis of existing research on fungal pathogens.
- Analysis of the impact of fungal toxins and diseases on agricultural output.
- Investigation into plant-based resistance mechanisms and antifungal compound discovery.
Main Results:
- Pathogenic fungi cause substantial economic losses in agriculture and pose risks to food safety.
- Emerging fungal pathogens, including Aspergillus and Fusarium species, cause severe human and animal diseases.
- Plants have evolved antifungal compounds as a defense mechanism against fungal infections.
Conclusions:
- Pathogenic fungi represent a significant global challenge to agricultural productivity and public health.
- Understanding fungal pathogenicity is crucial for developing effective disease management strategies.
- Plants offer a promising avenue for discovering natural antifungal agents to combat fungal infections.
Related Concept Videos
Overview of Fungi
Fungal Phylum Basidiomycota
Fungal Group Zygomycota
Microorganisms in Agriculture and Food industry
Fungal Phylum Ascomycota
Sources of Food Contamination
