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[Morphometry of sacral neurons innervating the pelvic muscles. Experimental study]
E Canon1, M Reznik, L M Timmermans
1Département d'Urologie, CHU-Vesale, Montigny le Tilleul.
Acta Urologica Belgica
|January 1, 1991
Summary
This study maps sacral motoneurons innervating rat pelvic muscles, revealing specific neuronal locations and morphological differences for muscles like the bulbo-spongiosus and sphincter ani. Findings provide a comparative reference for human pelvic muscle innervation.
Area of Science:
- Neuroscience
- Anatomy
- Physiology
Context:
- Sacral motoneurons innervating pelvic floor muscles are crucial for function.
- Limited information exists on the specific morphology and interconnection of these neurons.
- Previous studies primarily focused on general innervation patterns.
Purpose:
- To differentiate and map the neuronal origins of specific pelvic muscles in rats.
- To compare the morphology (diameter, surface area) of motoneurons innervating different pelvic muscles.
- To establish a detailed comparative reference for human pelvic muscle innervation.
Summary:
- Horse-radish-peroxidase (HRP) tracing was used to map motoneurons for bulbo-spongiosus (B.S.M.), ischio-cavernosus (I.C.M.), levator ani (L.A.M.), sphincter ani (S.A.M.), and sphincter urethrae (S.U.M.) muscles in rats.
- Most muscles received homolateral innervation, with B.S.M. and S.A.M. showing partial contralateral innervation.
- Distinct neuronal groups (D.M. and D.L.) and significant morphological differences in neuron diameter and surface area were identified for each muscle group.
Impact:
- Provides detailed mapping of sacral innervation for rat pelvic muscles.
- Offers novel insights into the morphological characteristics of motoneurons supplying specific pelvic muscles.
- Establishes a valuable comparative neuroanatomical reference for understanding human pelvic floor innervation and dysfunction.