Related Experiment Video
Updated: Jul 14, 2026

Seeding and Implantation of a Biosynthetic Tissue-engineered Tracheal Graft in a Mouse Model
Published on: April 1, 2019
Repair of long-segment congenital tracheal stenosis
Ji-Hyuk Yang1, Tae-Gook Jun, Kiick Sung
1Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-dong, Gangnam-gu, Seoul, Korea.
Insights
Congenital tracheal stenosis in children is challenging. Autograft or slide tracheoplasty offers excellent outcomes, while pericardial patch tracheoplasty shows poor results for long-segment tracheal stenosis.
Area of Science:
- Pediatric surgery
- Thoracic surgery
- Congenital anomalies
Background:
- Long-segment tracheal stenosis is a severe condition in infants and children.
- Complete tracheal rings are often associated with this condition.
- Associated cardiac anomalies are common in affected patients.
Purpose of the Study:
- To evaluate the effectiveness of different surgical techniques for congenital long-segment tracheal stenosis.
- To compare the outcomes of pericardial patch, tracheal autograft, and slide tracheoplasty.
Main Methods:
- Retrospective review of 12 pediatric patients with congenital tracheal stenosis (1996-2004).
- Surgical interventions included pericardial patch tracheoplasty (n=4), tracheal autograft tracheoplasty (n=6), and slide tracheoplasty (n=2).
- Patient outcomes, including mortality, ventilator support, hospital stay, and need for re-examination, were analyzed.
Main Results:
- Pericardial patch tracheoplasty resulted in 4 deaths (2 early, 2 late).
- Autograft and slide tracheoplasty showed excellent survival rates, with one late death from pneumonia after autograft.
- Autograft and slide tracheoplasty required shorter ventilator support and hospital stays compared to pericardial patch.
- Repeated bronchoscopies were more frequent after pericardial and autograft procedures.
Conclusions:
- Tracheal autograft and slide tracheoplasty are superior surgical options for long-segment tracheal stenosis in children.
- Pericardial patch tracheoplasty is associated with poor outcomes and should be avoided.
- These techniques provide excellent short- and long-term results for managing this complex pediatric airway condition.
Abstract:
Long-segment tracheal stenosis in infants and small children is difficult to manage and can be life-threatening. A retrospective review of 12 patients who underwent surgery for congenital tracheal stenosis between 1996 and 2004 was conducted. The patients' median age was 3.6 months. All patients had diffuse tracheal stenosis involving 40-61% (median, 50%) of the length of the trachea, which was suspected to be associated with complete tracheal ring. Five patients had proximal bronchial stenosis also. Ten patients had associated cardiac anomalies. Three different techniques were performed; pericardial patch tracheoplasty (n=4), tracheal autograft tracheoplasty (n=6), and slide tracheoplasty (n=2). After pericardial tracheoplasty, there were 2 early and 2 late deaths. All patients survived after autograft and slide tracheoplasty except one who died of pneumonia one year after the autograft tracheoplasty. The duration of ventilator support was 6-40 days after autograft and 6-7 days after slide tracheoplasty. The duration of hospital stay was 13-266 days after autograft and 19-21 days after slide tracheoplasty. Repeated bronchoscopic examinations were required after pericardial and autograft tracheoplasty. These data demonstrate that pericardial patch tracheoplasty show poor results, whereas autograft or slide tracheoplasty gives excellent short- and long-term results.
More Related Videos
Related Concept Videos
Trachea
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of the...
Tracheostomy Decannulation
Description of the Procedure
Decannulation refers to the permanent removal of the tracheostomy tube, signaling the resolution of the condition that initially necessitated the tracheostomy. The process requires a well-coordinated interplay between...
Tracheostomy: Procedure and Tubes
Tracheostomy tubes can be made of semiflexible plastic (polyurethane or silicone), rigid plastic, or metal, and they come in...
Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
Tracheostomy Care II: Procedure
Step 1: Perform hand hygiene, and put on personal protective equipment: gown, gloves, mask and...
Tracheostomy Care I: Pre-procedural Steps
Required Equipment
The equipment necessary for tracheostomy care includes:

