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Silencing E1A mRNA by RNA interference inhibits adenovirus replication

Y-S Chung1, M-K Kim, W-J Lee

  • 1Division of Influenza and Respiratory Viruses, Center for Infectious Disease, National Institute of Health, Korea Centers for Disease Control and Prevention, Seoul, South Korea.

Archives of Virology
|June 29, 2007
PubMed
Summary

Small interfering RNAs (siRNAs) targeting adenovirus E1A messenger RNA (mRNA) effectively inhibited adenovirus replication. This RNA interference (RNAi) approach shows potential as a novel antiviral therapy for adenovirus infections.

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