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Related Experiment Video

Updated: Jul 14, 2026

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
04:04

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection

Published on: August 15, 2025

Mandibular Caffey's disease--case report.

Ksenija Kovacić1, Tomislav F Hajnzić, Sanja Roncević

  • 1Department of Oncology and Nuclear Medicine, University Hospital Sestre Milosrdnice Zagreb, Croatia.

Collegium Antropologicum
|June 30, 2007
PubMed
Summary

Caffey's disease in infants can be diagnosed using bone scintigraphy. This imaging technique is crucial for identifying mandibular involvement, guiding treatment, and avoiding unnecessary procedures in suspected osteomyelitis cases.

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Area of Science:

  • Pediatric Radiology
  • Pediatric Orthopedics
  • Medical Imaging

Background:

  • Caffey's disease, also known as infantile cortical hyperostosis, is a rare condition presenting with bone overgrowth.
  • Early diagnosis is essential for appropriate management and to differentiate from other bone pathologies like osteomyelitis.
  • Mandibular involvement in Caffey's disease requires specific diagnostic considerations.

Observation:

  • A case study of a six-month-old boy with mandibular Caffey's disease is presented.
  • The initial clinical presentation mimicked osteomyelitis, prompting early diagnostic imaging.
  • Bone scintigraphy was performed as one of the initial investigations.

Findings:

  • Bone scintigraphy revealed a highly characteristic imaging pattern indicative of Caffey's disease affecting the mandible.

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Last Updated: Jul 14, 2026

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
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Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection

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  • The scintigraphic findings were instrumental in establishing the correct diagnosis.
  • This imaging modality played a pivotal role in guiding subsequent treatment decisions.
  • Implications:

    • Bone scintigraphy is a valuable, non-invasive tool for diagnosing mandibular Caffey's disease in infants.
    • Characteristic scintigraphic findings can expedite diagnosis and prevent misdiagnosis as osteomyelitis.
    • Accurate diagnosis through scintigraphy can help avoid unnecessary invasive procedures and guide effective therapeutic strategies.