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Related Experiment Video

Updated: Jul 14, 2026

Implantation of the Syncardia Total Artificial Heart

Implantation of the Syncardia Total Artificial Heart

Published on: July 18, 2014

Midterm experience with the Jarvik 2000 axial flow left ventricular assist device.

Saleem Haj-Yahia¹, Emma J Birks, Paula Rogers

¹Cardiothoracic Transplantation and Mechanical Circulatory Support, Royal Brompton & Harefield Hospital, London, UK.

The Journal of Thoracic and Cardiovascular Surgery

|June 30, 2007

Summary

The Jarvik 2000 intracardiac pump offers good intermediate-term outcomes for heart failure patients awaiting transplant or recovery. While it shows low infection and failure rates, bleeding complications are common due to anticoagulation.

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Published on: August 16, 2021

Area of Science:

Cardiology
Medical Devices
Surgical Technology

Background:

Rotary axial flow pumps present unique advantages and disadvantages compared to pulsatile pumps.
The Jarvik 2000 is an intracardiac rotary axial flow pump.
This study evaluates the clinical experience with the Jarvik 2000 in a patient cohort.

Purpose of the Study:

To assess the efficacy and safety of the Jarvik 2000 intracardiac pump.
To report outcomes in patients receiving the Jarvik 2000 as a bridge to transplant or myocardial recovery.
To identify potential complications associated with Jarvik 2000 support.

Main Methods:

The Jarvik 2000 was implanted in 22 patients (15 male, 7 female) with advanced heart failure.
Preoperative conditions included dilated cardiomyopathy, postpartum cardiomyopathy, ischemic heart disease, and allograft failure.
Patients presented with severe symptoms (NYHA Class IV) and required significant medical or mechanical support.

Main Results:

There were 8 deaths (2 early, 6 late) among the 22 patients.
The device provided support for a mean duration of 280.5 days (total 6172 days).
Key complications included bleeding events (n=3) and driveline issues (n=3), with no pump infections or failures reported.

Conclusions:

The Jarvik 2000 demonstrates satisfactory intermediate-term results for bridging patients to transplant or recovery.
The device is associated with a low incidence of serious pump or driveline infections and technical failures.
Bleeding complications, attributed to anticoagulation, represent a significant concern requiring careful management.