Related Experiment Video
Updated: Jul 14, 2026

Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model
Published on: June 6, 2025
Treating tobacco dependence in clinically depressed smokers: effect of smoking cessation on mental health functioning
Judith J Prochaska1, Sharon M Hall, Janice Y Tsoh
1University of California-San Francisco, 401 Parnassus Ave, Box TRC-0984, San Francisco, CA 94143-0984, USA. jprochaska@ucsf.edu
Abstract:
We analyzed data from a randomized trial of 322 actively depressed smokers and examined the effect of smoking cessation on their mental health functioning. Only 1 of 10 measures at 4 follow-up time points was significant: participants who successfully stopped smoking reported less alcohol use than did participants who continued smoking. Depressive symptoms declined significantly over time for participants who stopped smoking and those who continued smoking; there were no group differences. Individuals in treatment for clinical depression can be helped to stop smoking without adversely affecting their mental health functioning.
Related Concept Videos
CNS Depressants: Alcohol and Nicotine
Stress Prevention and Stress Management Techniques IV
Drug Dependence
Antidepressant Drugs: MAOIs and Other Agents
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Depressive Disorders: MDD and Dysthymia