Related Experiment Video
Updated: Jul 14, 2026

Isolation and Quantification of Botulinum Neurotoxin From Complex Matrices Using the BoTest Matrix Assays
Published on: March 3, 2014
[Manktelow's test for the use of botulic toxin]
P Guerreschi1, D Labbé, L Carluer
1Service Chirurgie Maxillofaciale etPlastique, CHRU de Caen, avenue Côte-de-Nacre, 14033 Caen cedex 05, France. pierre.guerreschi@wanadoo.fr
Abstract:
We are reporting the use of a xylocain test before the injection of botulinal toxin within the "facial paralysis and botulinal toxin" multidisciplinary consultation of the Caen regional hospital. Our assessment is about 16 patients tested. This test is based on a digital film and a questionnaire. It is often proposed when toxin is first used. It influences the patient's choice. It permits a better understanding of the toxin action by the patient, it reassures. It is reliable for the practitioner even though we do not have a mathematical correlation between the xylocain volume and the botulinal toxin volume. Simple and far, it is a help for the patient and the practitioner before a delicate injection of botulinal toxin.
Related Concept Videos
Directly Acting Muscle Relaxants: Dantrolene and Botulinum Toxin
The binding of dantrolene to the RYR1...
Botulism
Myasthenia Gravis: Diagnostic Tests
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
Skeletal Muscle Relaxants: Therapeutic Uses
