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Risk factors for chronic venous disease: the San Diego Population Study
Michael H Criqui1, Julie O Denenberg, John Bergan
1Department of Family and Preventive Medicine, University of California, San Diego, CA, USA. mcriqui@ucsd.edu
Journal of Vascular Surgery
|June 30, 2007
Summary
Chronic venous disease risk factors include age, family history, and lifestyle choices like weight and physical activity. Modifying these factors may help prevent venous disease.
Area of Science:
- Vascular Medicine
- Epidemiology
- Public Health
Background:
- The causes of chronic venous disease (CVD) in the lower limbs are not well understood.
- Limited data exist on potential risk factors from population-based studies.
Purpose of the Study:
- To systematically assess potential risk factors for venous disease in a representative adult population.
- To identify independent predictors for moderate and severe venous disease.
Main Methods:
- The San Diego Population Study assessed randomly selected adults for venous disease risk factors.
- Disease severity was categorized using clinical examination and ultrasonography.
- Questionnaires and examinations collected data on potential risk factors.
Main Results:
- Age, family history, hernia surgery, and normotension were linked to moderate venous disease.
- Weight, physical activity, childbirths, and certain conditions predicted venous disease in men and women.
- African American ethnicity showed a protective effect for severe venous disease in women.
Conclusions:
- Some venous disease risk factors like age and genetics are immutable.
- Modifiable factors include weight, physical activity, and smoking.
- Behavioral modifications may offer potential for preventing chronic venous disease.
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