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Mist delivery of eye medication to the anterior segment
James F Collins1, Darlene A Dartt, Reza Dana
1Stony Brook University School of Medicine, Stony Brook, New York, USA. optimystsystem@gmail.com
Purpose:
To compare the mydriatic efficacies of mist and drop delivery of tropicamide 1.0%.
Design:
Randomized, masked, active, controlled clinical trial.
Methods:
One hundred subjects were randomized to receive small-volume (6 microl) mist administration of tropicamide 1.0% in one eye and either nothing or a conventional drop (30 microl) of the same solution in the fellow eye.
Results:
Comparing misted eyes with untreated eyes in the same subjects, the mean maximal increase in pupil diameter in the misted eyes was 2.02 mm and was 0.25 mm in the fellow eyes. The difference is statistically significant (P
Conclusions:
Small-volume mist and conventional drop delivery of tropicamide 1.0% were shown to be similar in mydriatic effectiveness.
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