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Updated: Aug 17, 2026

Preparation and Characterization of Individual and Multi-drug Loaded Physically Entrapped Polymeric Micelles
Published on: August 28, 2015
Computation of release kinetics of isoniazid microcapsules
Abstract:
Isoniazid is a drug of choice for intermittent chemotherapy of tuberculosis. It has been microencapsulated by emulsification followed by solvent evaporation technique using Eudragit RS 100 as polymer where free flowing, spherical and discrete microcapsules have been formed as obtained by SEM. The drug release data have been computed in the light of various kinetic models, where it is found that the matrix release mechanism predominates over the first and zero order mechanism for isoniazid microcapsules, even if the sizes and drug polymer ratio of the microcapsules were varied.
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