Related Experiment Videos
Analysis of the activation of poly(ADP-ribose) polymerase by various types of DNA
C Hengartner1, J Lagueux, G G Poirier
1Poly (ADP-ribose) Metabolism Group, CHUL Research Center and Laval University, Ste-Foy, Que., Canada.
Abstract:
In this work, we examined the activation of poly(ADP-ribose) polymerase by various types of DNA. We have found that the best activator for poly(ADP-ribose) polymerase is an octanucleotide. However, the use of a defined activated DNA is also suitable.