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Related Experiment Videos

Anal infections caused by herpes simplex virus.

E Jacobs

    Diseases of the Colon and Rectum
    |March 1, 1976
    PubMed
    Summary

    Anal herpes, caused by the herpes simplex virus type 2 (HSV-2), is an increasingly common sexually transmitted infection. Diagnosis is typically clinical, and while self-limiting, it can be recurrent and painful.

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    Area of Science:

    • Infectious Diseases
    • Dermatology
    • Virology

    Background:

    • Herpes simplex virus type 2 (HSV-2) commonly causes perianal and anal canal infections.
    • Anogenital herpes is a sexually transmitted disease, often transmitted via anal intercourse.
    • The prevalence of anal herpes appears to be increasing in society.

    Purpose of the Study:

    • To report on a series of 16 cases of perianal and anal herpes.
    • To highlight the clinical presentation, diagnosis, and potential treatments for anal herpes.

    Main Methods:

    • Clinical diagnosis based on characteristic vesicles, aphthous ulcers, and inguinal lymphadenopathy.
    • Laboratory confirmation using cytology, immunofluorescence, viral cultures, and serologic tests.
    • Review of treatment modalities, including experimental approaches.

    Main Results:

    • Anal herpes infections, though underreported, are not uncommon.
    • Primary infections inside the anal canal can cause debilitating pain.
    • Asymptomatic individuals, particularly homosexual men, may serve as significant reservoirs for HSV-2 transmission.

    Conclusions:

    • Anal herpes is a clinically recognizable condition, often associated with HSV-2.
    • The disease is typically self-limiting but prone to recurrence.
    • Promising new treatments, including vaccines and photoinactivation therapy, are under investigation.

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