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Updated: Jul 14, 2026

Superior Auto-Identification of Trypanosome Parasites by Using a Hybrid Deep-Learning Model
Published on: October 27, 2023
Trypanosoma brucei 29-13 strain is inducible in but not permissive for the tsetse fly vector
Stéphane Herder1, Jan Votýpka, Milan Jirků
1UMR 177 IRD CIRAD, Campus International de Baillarguet, 34398 Montpellier Cedex 5, France.
Abstract:
Using green fluorescent protein as a reporter, we have shown that the strain 29-13 of Trypanosoma brucei, widely used for inducible down-regulation of mRNA, is inducible in, but not permissive for the tsetse flies Glossina palpalis gambiensis and Glossina morsitans morsitans. Within two weeks post-infection, 42% males and females of teneral and non-teneral tsetse flies harboured intestinal infections, yet not a single infection progressed into the salivary glands.

