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Antibacterial multifilament nylon sutures.

J P Singhal1, J Singh, A R Ray

  • 1Centre for Biomedical Engineering, Indian Institute of Technology, New Delhi, India.

Biomaterials, Artificial Cells, and Immobilization Biotechnology : Official Journal of the International Society for Artificial Cells and Immobilization Biotechnology
|January 1, 1991
PubMed
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Antibacterial nylon fibers were created by doping with iodine. These iodine-doped fibers show sustained antibacterial activity against common bacteria, releasing tri-iodide ions over 30 days.

Area of Science:

  • Materials Science
  • Textile Engineering
  • Microbiology

Background:

  • Nylon fibers are widely used but lack inherent antimicrobial properties.
  • Developing effective antimicrobial textiles is crucial for healthcare and public hygiene.

Purpose of the Study:

  • To create antibacterial nylon fibers through iodine doping.
  • To evaluate the antibacterial efficacy and iodine release characteristics of doped fibers.

Main Methods:

  • Nylon fibers were immersed in an acetone-iodine solution for 48 hours.
  • Antibacterial activity was assessed using the zone of inhibition assay against four bacterial species.
  • Iodine release kinetics and ion speciation were analyzed using spectroscopy.

Main Results:

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  • Iodine uptake increased with higher iodine concentrations.
  • Doped fibers demonstrated significant antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Klebsiella pneumoniae.
  • Sustained iodine release occurred for approximately 30 days, with tri-iodide ions identified as the active antibacterial agent.

Conclusions:

  • Iodine doping is an effective method for imparting antibacterial properties to nylon fibers.
  • The sustained release of tri-iodide ions provides long-lasting antimicrobial protection.
  • Iodine doping causes minor fiber shrinkage but does not significantly affect breaking load.