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Updated: Jul 14, 2026

Minimally Invasive Murine Laryngoscopy for Close-Up Imaging of Laryngeal Motion During Breathing and Swallowing
Published on: December 1, 2023
[Glottis morphology in rheumatoid arthritis]
Katarzyna Amernik1, Czesława Tarnowska, Iwona Brzosko
1Katedra i Klinika Otolaryngologii i Onkologii Laryngologicznej PAM w Szczecinie.
Rheumatoid arthritis can affect the larynx, causing symptoms like throat discomfort and hoarseness. Early detection of these laryngeal changes in rheumatoid arthritis patients is crucial for timely intervention.
Area of Science:
- Rheumatology
- Otolaryngology
- Inflammatory Diseases
Context:
- Rheumatoid arthritis (RA) is a systemic inflammatory disease.
- RA can affect various joints, including the cricoarytenoid (CA) joints in the larynx.
- Laryngeal involvement in RA can lead to significant patient morbidity.
Purpose:
- To assess glottis morphology and the frequency of laryngeal structure involvement in RA patients.
- To evaluate patient complaints indicative of laryngeal involvement in RA.
- To correlate laryngeal findings with disease activity and patient symptoms.
Summary:
- 77 RA patients (mean age 56.69) were evaluated using clinical examination, videolaryngoscopy, CT, and EMG.
- Common complaints included foreign body sensation (51%) and hoarseness (47%).
- Videolaryngoscopy revealed CA area mucosal swelling/redness in 45%; vocal fold immobility occurred in 3 patients, necessitating tracheotomy in one case. Active RA and throat sensation correlated with laryngeal inflammation.
Impact:
- Rheumatoid inflammation of the larynx manifests as CA area mucosal changes and potential vocal fold immobilization.
- Throat sensation and hoarseness during RA flares may signal laryngeal involvement.
- Findings support continued monitoring of laryngeal changes in peripheral RA patients.
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