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Related Concept Videos

Assessment of the Mouth01:26

Assessment of the Mouth

A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Oral Cavity01:11

Oral Cavity

The oral cavity, or the mouth, is a complex structure in humans that plays a vital role in our day-to-day lives. Its role is not only in chewing and swallowing food; it also plays a role in speech and facial expressions.
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
Cancer02:18

Cancer

Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...

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Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

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American Association of Oral and Maxillofacial Surgeons' Position Paper on the Management of the Clinically Negative Neck (cN0) in cT1N0 and cT2N0 Oral Squamous Cell Carcinoma.

Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons·2026
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American Dental Association and American Academy of Oral and Maxillofacial Radiology patient selection for dental radiography and cone-beam computed tomography: Clinical recommendations.

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Perspective on trends in oral and maxillofacial surgery residency training and recent match results.

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Common Local and Regional Flaps for the Maxillary and Midface.

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Related Experiment Video

Updated: Jul 14, 2026

Isolation of Cells with Morphological and Spatial Information from Oral Submucous Fibrosis Samples by Laser Capture Microdissection
05:42

Isolation of Cells with Morphological and Spatial Information from Oral Submucous Fibrosis Samples by Laser Capture Microdissection

Published on: August 11, 2023

Oral cancer.

Deepak Kademani1

  • 1Division of Oral Diagnosis and Oral and Maxillofacial Surgery, Mayo Clinic, 200 First St SW, Rochester, Minn 55905, USA. kademani.deepak@mayo.edu

Mayo Clinic Proceedings
|July 4, 2007
PubMed
Summary

Oral cancer, a significant cause of cancer mortality, often presents with nonspecific symptoms. Early detection through routine screening is crucial for improving patient survival rates.

Area of Science:

  • Oncology
  • Public Health

Background:

  • Head and neck tumors account for 5% of all tumors, with oral cavity tumors representing half of these.
  • Oral cavity squamous cell carcinomas constitute a substantial portion of head and neck cancers globally and in the US.
  • Oral cancer remains a leading cause of cancer mortality, with a significant number of deaths occurring annually in the United States.

Purpose of the Study:

  • To highlight the incidence and mortality of oral cancer.
  • To emphasize the challenge of late-stage diagnosis due to nonspecific symptoms.
  • To advocate for increased awareness and routine screening by primary care physicians, especially in younger populations without traditional risk factors.

Main Methods:

  • Analysis of global tumor incidence data.
  • Review of Surveillance, Epidemiology, and End Results (SEER) Program data for the United States.

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Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way
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Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way

Published on: May 10, 2021

Related Experiment Videos

Last Updated: Jul 14, 2026

Isolation of Cells with Morphological and Spatial Information from Oral Submucous Fibrosis Samples by Laser Capture Microdissection
05:42

Isolation of Cells with Morphological and Spatial Information from Oral Submucous Fibrosis Samples by Laser Capture Microdissection

Published on: August 11, 2023

Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way
04:45

Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way

Published on: May 10, 2021

  • Clinical observation of patient presentation and diagnostic challenges.
  • Main Results:

    • Oral cancer accounts for a significant number of new cases and deaths annually in the US.
    • A considerable percentage of patients are diagnosed with advanced-stage oral cancer.
    • Nonspecific clinical signs and symptoms often lead to misdiagnosis or delayed diagnosis.

    Conclusions:

    • Primary care physicians must maintain a high index of suspicion for oral cancer, even in young patients lacking typical risk factors.
    • Routine and vigilant screening for oral mucosal lesions is essential for early detection and improved survival outcomes.
    • Despite advances in medical technology, challenges in early oral cancer detection persist, necessitating enhanced screening protocols.