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Related Experiment Videos

Restenosis after eversion vs patch closure carotid endarterectomy.

Robert S Crawford1, Thomas K Chung, Thomas Hodgman

  • 1Division of Vascular and Endovascular Surgery of the General Surgical Services, Massachusetts General Hospital and Harvard Medical School, 15 Parkman Street, Boston, MA 02114, USA.

Journal of Vascular Surgery
|July 4, 2007
PubMed
Summary
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Recurrent stenosis after carotid endarterectomy (CEA) is a limitation. Eversion CEA (EV) and patch closure (PC) showed similar restenosis rates, suggesting biological factors, not technique, influence recurrence. EV adoption for lower restenosis is not warranted.

Area of Science:

  • Vascular Surgery
  • Cardiovascular Research

Background:

  • Recurrent stenosis after carotid endarterectomy (CEA) limits its long-term efficacy.
  • Eversion endarterectomy (EV) is perceived to have lower restenosis rates than patch closure (PC), but evidence is conflicting.

Purpose of the Study:

  • To compare the late anatomic results of patch closure (PC) versus eversion CEA (EV).

Main Methods:

  • A retrospective study of 950 CEAs performed between 1995 and 2005.
  • 155 PC and 135 EV patients with at least 1-year follow-up were analyzed.
  • Incidence of moderate (50-70%) and severe (>70%) restenosis, late stroke, survival, and reintervention rates were assessed.

Main Results:

  • No significant differences in demographic/clinical parameters or perioperative outcomes between PC and EV.

Related Experiment Videos

  • Actuarial analysis revealed no significant difference in late moderate or severe restenosis rates between PC and EV.
  • Female gender was associated with increased risk of severe restenosis and late stroke, irrespective of surgical technique.
  • Conclusions:

    • Restenosis rates after CEA are similar between eversion and patch closure techniques.
    • Restenosis appears to be a biological remodeling phenomenon rather than a result of technical variations.
    • Adopting eversion CEA solely to decrease restenosis is not supported by these findings.