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Updated: Jul 14, 2026

In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells
10:26

In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells

Published on: January 20, 2019

The effects of microenvironment and internal programming on plasma cell survival

Heather A Minges Wols1, Jill A Ippolito, Zheng Yu

  • 1Department of Science and Mathematics, Columbia College Chicago, Chicago, IL 60605, USA. hwols@colum.edu

International Immunology
|July 4, 2007
PubMed
Summary

Plasma cell (PC) longevity is determined by their environment, not intrinsic factors. Bone marrow stromal cells uniquely support long-lived plasma cells, but the exact mechanisms remain unknown.

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