[Study on the interactions between rhizoma coptidis and radix glycyrrhiza]

Ancient prescription rhiaoma coptidis powder is a kind of traditional Chinese medicine compounds (TCMC) which is composed of rhizoma coptidis (RC) and radix glycyrrhiza (RG). In the present investigation, the compositions in solutions and precipitates of single decocted RC and RG, and decocted RC-RG mixture were studied by FTIR spectroscopy, HPLC technique and TOF-MS method. The components of decocted RC-RG mixture are different from those of the addition of RC and RG, suggesting that the interactions between RC and RG occurred. The results of FTIR spectroscopic characterization, and HPLC and TOF-MS measurements demonstrated that in both solutions and precipitates some new chemical compounds formed, while some components in the original single decocted RC and RG were restrained in the mixed system, indicating that RG plays an important role in this TCMC-rhizoma coptidis powder.