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11:14
Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture
Published on: October 12, 2018
HIV, cutaneous larva migrans and fever
1Institute of Dermatological Sciences, University of Milan, Milan, Italy. stefano.veraldi@unimi.it
International Journal of STD & AIDS
|July 5, 2007
Summary
Fever in patients with cutaneous larva migrans may indicate HIV infection. This finding is based on two HIV-positive cases where other fever causes were ruled out.
Area of Science:
- Dermatology
- Infectious Diseases
- Virology
Background:
- Cutaneous larva migrans (CLM) is a parasitic skin infection.
- Human Immunodeficiency Virus (HIV) infection can present with various dermatological manifestations.
- Fever is a common but non-specific symptom in immunocompromised individuals.
Observation:
- Two cases of CLM were observed in HIV-positive patients presenting with fever.
- Extensive laboratory and instrumental investigations were performed.
- Other potential causes for the fever were systematically excluded.
Findings:
- The presented cases suggest a potential association between fever and CLM in the context of HIV infection.
- CLM in HIV-positive individuals may manifest with fever, even in the absence of other opportunistic infections.
- The exclusion of alternative etiologies strengthens the link between CLM and fever in these specific cases.
Implications:
- Fever in patients diagnosed with CLM could serve as an early indicator for underlying HIV infection.
- This association warrants further investigation to understand the pathomechanisms involved.
- Clinicians should consider HIV testing in patients presenting with CLM and unexplained fever, particularly in endemic areas.
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