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Published on: March 3, 2023
Hepatic resection for colorectal liver metastases
1Department of Surgery, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China. josephlau@cuhk.edu.hk
Singapore Medical Journal
|July 5, 2007
Summary
Liver resection offers curative treatment for colorectal carcinoma patients with liver metastases. This study shows hepatic resection provides good long-term survival with acceptable risks, improving outcomes for these patients.
Area of Science:
- Oncology
- Surgical Oncology
- Hepatobiliary Surgery
Background:
- Colorectal carcinoma frequently metastasizes to the liver, often leading to mortality.
- Liver resection is the only curative option for liver-confined metastases.
- Current resectability rates are low, necessitating improved strategies for colorectal liver metastases.
Purpose of the Study:
- To evaluate the outcomes of hepatic resection for colorectal liver metastases.
- To assess the feasibility and efficacy of salvage surgery for initially unresectable disease.
- To analyze survival rates and complications associated with liver resection.
Main Methods:
- Retrospective study of patients with colorectal liver metastases undergoing liver resection.
- Data collected from January 1998 to December 2002 at a tertiary surgical center.
- Analysis included primary resection, salvage surgery after downstaging, and repeat resection for recurrence.
Main Results:
- 42 patients underwent hepatic resection; 36 had primary resection, 6 received salvage surgery.
- Hospital mortality was 2.1%, with 11.9% major postoperative complications.
- Median survival was 49 months; 5-year survival was 37% for primary resection, 34% for salvage, and 27% for repeat resection.
Conclusions:
- Hepatic resection for colorectal liver metastases yields good long-term survival.
- Operative mortality and morbidity are acceptably low.
- Results align with international standards for liver resection in this patient population.
