Related Experiment Video
Updated: Jul 13, 2026

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
Published on: March 11, 2021
[Determination of organ doses and effective doses in radiooncology]
Jakob Roth1, Aurélien Emmanuel Martinez
1Radiologische Physik, Radio-Onkologie, Universitätsspital, 4031, Basel, Schweiz. jroth@uhbs.ch
Background And Purpose:
With an increasing chance of success in radiooncology, it is necessary to estimate the risk from radiation scatter to areas outside the target volume. The cancer risk from a radiation treatment can be estimated from the organ doses, allowing a somewhat limited effective dose to be estimated and compared.
Material And Methods:
The doses of the radiation-sensitive organs outside the target volume can be estimated with the aid of the PC program PERIDOSE developed by van der Giessen. The effective doses are determined according to the concept of ICRP, whereby the target volume and the associated organs related to it are not taken into consideration.
Results:
Organ doses outside the target volume are generally < 1% of the dose in the target volume. In some cases, however, they can be as high as 3%. The effective doses during radiotherapy are between 60 and 900 mSv, depending upon the specific target volume, the applied treatment technique, and the given dose in the ICRU point.
Conclusion:
For the estimation of the radiation risk, organ doses in radiooncology can be calculated with the aid of the PC program PERIDOSE. While evaluating the radiation risk after ICRP, for the calculation of the effective dose, the advanced age of many patients has to be considered to prevent that, e.g., the high gonad doses do not overestimate the effective dose.
Related Concept Videos
Dose Size and Dosing Frequency: Determination Methods
Biological Effects of Radiation
Determination of Multiple Dosing Parameters: Loading and Maintenance Doses
Drug Dosing in Renal Diseases: Dose Adjustments Based on Drug Clearance and Elimination Rate Constant
Isotopes and Radioisotopes
An isotope containing more...
Dosage Interval and Administration Route: Determination Methods
