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An Orthotopic Bladder Tumor Model and the Evaluation of Intravesical saRNA Treatment
Published on: July 28, 2012
[Low-dose rate brachytherapy with locally integrated beta emitters after internal urethrotomy. A pilot project using
1Urologische Klinik und Poliklinik, Klinikum der Universität München-Grosshadern, Marchioninistrasse 15, 81377 München. Patrick.Weidlich@med.uni-muenchen.de
Background:
The treatment of urethral strictures represents an unsolved urological problem.
Patients And Methods:
The effect of a (32)P-coated urethral catheter in the sense of low-dose rate brachytherapy to modulate wound healing will be analyzed in an animal experiment.
Results:
Unfortunately it is not possible to present any results because this is being studied for the first time and there are no experiences with low-dose rate brachytherapy and this form of application in the lower urinary tract. Furthermore the animal experiment will only start in the near future. Both decade-long experiences with radiotherapy to treat benign diseases and our own results of previous studies in otolaryngology and ophthalmology let us expect a significantly lower formation of urethral strictures after internal urethrotomy.
Conclusion:
This study will contribute to improving the treatment of urethral strictures as demanded in previous papers.

