Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Skin friction blistering: computer model.

Malcolm Xing1, Ning Pan, Wen Zhong

  • 1Department of Biological System Engineering, University of California, Davis, CA, USA.

Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [And] International Society for Digital Imaging of Skin (ISDIS) [And] International Society for Skin Imaging (ISSI)
|July 6, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluation of nucleic acid-based matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for rapid identification of <i>Mycobacterium tuberculosis</i> and drug resistance in patients with retreatment tuberculosis.

Frontiers in microbiology·2026
Same author

Aberrant multivariate mapping between behavioral profiles and cortical morphological brain networks in children with autism spectrum disorder.

Translational psychiatry·2026
Same author

Inflammatory myofibroblasts reprogram neutrophil fate to drive chronic inflammation in peri-implantitis.

International journal of oral science·2026
Same author

Corrigendum to "Development and Validation of a Risk Prediction Model for Postoperative Pulmonary Infection in Renal Transplant Patients" Transplantation Proceedings, 58(2026), 511-519.

Transplantation proceedings·2026
Same author

Thymosin Alpha-1 Restores Chemotherapy-Induced Antitumor Immunity by Chaperoning a MicroRNA Ligand of TLR7 in Dendritic Cells.

Cancer research·2026
Same author

Mapping the Invisible Landscape of Pesticides and Adjuvants in Peri-Urban Agricultural Waterways of the Megacity Shanghai.

Environmental science & technology·2026
Same journal

Noninvasive Diagnosis Revealed a Strong Therapeutic Response and Skin Barrier Changes in Hemoporfin-Mediated Photodynamic Therapy for Port-Wine Stains.

Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·2026
Same journal

In Vivo Microscopic Features of Acne vulgaris Revealed via LC-OCT.

Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·2026
Same journal

Intravital Monitoring of Psoriasis Treatment Response and Drug Delivery Using Multiphoton Fluorescence Lifetime Imaging.

Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·2026
Same journal

Retinol-Loaded Mannosylerythritol Lipid Nanoliposome for Enhanced Human Skin Penetration.

Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·2026
Same journal

Artificial Intelligence in Dermatology: New Regulatory Aspects After the European AI Act.

Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·2026
Same journal

Reduction of Ultraviolet- and Heat-Induced Aging Using Betulin-Loaded Arginine-Caprylate Self-Assembly: Randomized Double-Blind Clinical Trials.

Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·2026
See all related articles

Computer modeling of friction blisters reveals loading frequency significantly impacts stress and deformation. Optimal friction coefficients can reduce blister severity, while contact material stiffness has minimal effect.

Area of Science:

  • Biomechanics
  • Materials Science
  • Computational Modeling

Background:

  • Friction blisters are common injuries in sports and military settings, impacting performance.
  • Studying blisters is challenging due to difficulties in human and animal experimentation.
  • Blistering can be modeled as a delamination phenomenon, drawing parallels with materials science.

Purpose of the Study:

  • To investigate the effects of friction coefficient and contact material stiffness on blister deformation and stress using computational modeling.
  • To explore the relationship between loading frequency and blister characteristics.

Main Methods:

  • A dynamic non-linear finite-element model was developed.
  • The model incorporated a blister-characterized structure and contact algorithms.

Related Experiment Videos

  • Simulations varied friction coefficient, elastic modulus, and loading frequency.
  • Main Results:

    • Loading frequency significantly alters displacement and stress.
    • Increased friction coefficient does not always increase stress or deformation; local maxima exist.
    • Contact material stiffness showed no significant effect on deformation or stress within the tested range.

    Conclusions:

    • The finite-element model effectively predicts the influence of friction and stiffness on blisters.
    • Findings can inform strategies for reducing blister incidents by evaluating loading conditions and materials.