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Published on: May 10, 2024
[A case of alpha-fetoprotein-producing minute mucosal gastric cancer]
Shoji Hirasaki1, Junro Kataoka, Junichirou Nasu
1Second Department of Internal Medicine, Sumitomo Besshi Hospital.
Abstract:
The endoscopic examination of a 63-year-old man revealed a IIc lesion, 5 mm in diameter, in the lesser curvature of the gastric body. His serum alpha-fetoprotein (AFP) level was high at 14.3 ng/ml. Immunohistological studies on the biopsy specimens showed a positive reaction for AFP. Endoscopic ultrasonography revealed that the tumor was limited to the second layer of the gastric wall and this tumor was diagnosed as mucosal cancer. The final diagnosis was AFP-producing mucosal gastric cancer (AFPMGC). Cases of AFPMGC are rarely encountered. The present case suggested that even minute mucosal gastric cancer could produce AFP.
