Methods of reconstruction of large bone defects after tumor resection

Large bone defects resulting from the resection of tumors and tumor-like lesions must be repaired. The method of reconstruction depends on the diagnosis and the tumor location. Post-resection endoprostheses or large allografts are used routinely for primary neoplasms. Major surgical procedures and implants enhance deep infections. Loosening of the endoprostheses and the graft fractures appear in the later postoperative period. Methyl metacrylate is used in the treatment of bone metastases. Tumor-like defects are filled up after resection with morselized bone grafts.