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Updated: Jul 13, 2026

Generation and Culturing of Primary Human Keratinocytes from Adult Skin
10:42

Generation and Culturing of Primary Human Keratinocytes from Adult Skin

Published on: December 22, 2017

PPAR and LXR activators regulate ABCA12 expression in human keratinocytes

Yan J Jiang1, Biao Lu, Peggy Kim

  • 1Metabolism Section, Department of Veterans Affairs Medical Center, Northern California Institute for Research and Education, University of California at San Francisco, San Francisco, California 94121, USA. yan.jiang@med.va.gov

The Journal of Investigative Dermatology
|July 6, 2007
PubMed
Summary

Peroxisome proliferators-activated receptors (PPARs) and liver X receptor (LXR) activators boost ABCA12 expression in skin cells. This enhances the skin barrier, potentially aiding in treating ichthyosis disorders.

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