Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Myocarditis I: Introduction

Myocarditis I: Introduction

Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...

Myocarditis III: Medical Management

Myocarditis III: Medical Management

Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...

Myocarditis II: Clinical Features and Diagnostic Tests

Myocarditis II: Clinical Features and Diagnostic Tests

Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...

Myocarditis IV: Nursing Management

Myocarditis IV: Nursing Management

Myocarditis is an inflammatory condition of the myocardium requiring meticulous nursing management for optimal patient outcomes. Effective management begins with a thorough assessment of the patient's medical history, paying close attention to past infections, autoimmune disorders, travel history, and exposure to toxins or drugs. Recent viral infections and systemic diseases are particularly relevant due to their potential role in triggering myocarditis.Physical Examination and MonitoringThe...

Cardiomyopathy IV: Restrictive Cardiomyopathy

Cardiomyopathy IV: Restrictive Cardiomyopathy

Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...

Cryptococcal Meningitis

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Kynurenine Pathway Metabolite Levels in Drug Naïve and Risperidone Treated Schizophrenia: Insights From Systemic and Post-Mortem Brain Tissue Analysis.

Journal of neurochemistry·2026

Same author

Effect of Add-on Yoga-Based Intervention on Schizophrenia: A Randomized Controlled Trial.

Behavioral medicine (Washington, D.C.)·2026

Same author

The Brief Prakriti Inventory: Latent structure, reliability, and validity.

Wellcome open research·2026

Same author

Ayurvedic Therapeutic Regimen as an Add-On to Optimized Conventional Management of Parkinson Disease: Protocol for an Exploratory Randomized Controlled Trial Evaluating Clinical, Cortical Excitability, Neuroimmune, and Autonomic Function Parameters.

JMIR research protocols·2026

Same author

Yoga for Opioid Withdrawal and Autonomic Regulation: A Randomized Clinical Trial.

JAMA psychiatry·2026

Same author

Exploring Ayurveda's Potential in Parkinson's Disease: A Comprehensive Narrative.

Cureus·2025

Search research articles

Related Experiment Videos

Acute myocarditis associated with clozapine.

Shivarama Varambally¹, Padmini Howpage

¹Macquarie Hospital, Northern Sydney Central Coast Area Mental Health Service, NSW, Australia.

Australasian Psychiatry : Bulletin of Royal Australian and New Zealand College of Psychiatrists

|July 7, 2007

Summary

A case study highlights acute myocarditis, a potentially fatal complication, occurring shortly after starting clozapine treatment. Early recognition and awareness are crucial for managing this adverse effect in schizophrenia patients.

Related Experiment Videos

Area of Science:

Cardiology
Psychiatry
Pharmacology

Background:

Clozapine is a critical treatment for treatment-resistant schizophrenia.
Myocarditis is a serious cardiac complication associated with certain medications.

Observation:

A 20-year-old male with schizophrenia developed acute myocarditis.
Symptoms emerged approximately two weeks after initiating clozapine therapy.
Concomitant antidepressant use and physical exertion may have contributed.

Findings:

The patient recovered with intensive medical intervention.
This case underscores the risk of clozapine-induced myocarditis.

Implications:

Increased awareness of clozapine-associated myocarditis is vital for healthcare professionals.
Prompt diagnosis and management are essential to prevent fatal outcomes.
Regulatory and clinical practice recommendations for clozapine use may need review.