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Severe aortic stenosis and its association with hypertension: analysis of clinical and echocardiographic parameters

Katerina Linhartová1, Jan Filipovský, Roman Cerbák

  • 1Department of Cardiology, Cardiovascular Center, University Hospital Motol, Prague, Czech Republic. linhartkaterina@atlas.cz

Blood Pressure
|July 7, 2007
PubMed

Insights

Hypertension is common in severe aortic stenosis (AS) but does not affect ascending aortic dimensions. Bicuspid aortic valve and AS severity independently predict aortic size, not hypertension history.

Area of Science:

  • Cardiology
  • Vascular Biology
  • Cardiac Surgery

Background:

  • Aortic stenosis (AS) and hypertension commonly cause cardiac hypertrophy and aortic dilatation.
  • The combined effect on ascending aortic dimensions remains unevaluated.

Purpose of the Study:

  • To assess the impact of coincident hypertension on ascending aortic dimensions in patients with severe aortic stenosis.

Main Methods:

  • Cross-sectional analysis of clinical, angiographic, and echocardiographic data.
  • Included 225 patients undergoing evaluation for non-rheumatic AS.
  • Compared patients with and without hypertension.

Main Results:

  • Hypertension (68%) was associated with more severe dyspnea and higher coronary artery disease prevalence.
  • Ascending aortic dimensions, left ventricular mass, and remodeling were similar between hypertensive and normotensive groups.
  • Bicuspid aortic valve and stenosis severity independently predicted wider ascending aortic dimensions.

Conclusions:

  • Hypertension is prevalent in severe AS but does not independently influence ascending aortic dimensions.
  • Bicuspid aortic valve and AS severity are key determinants of ascending aortic size.
  • Findings suggest focusing on valve morphology and stenosis severity for aortic dimension assessment in AS.
Abstract

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