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Primary ventriculitis caused by Streptococcus intermedius.

G V Vajramani1, H Akrawi, G Jones

  • 1Department of Neurosurgery, Southampton General Hospital, Southampton, UK.

British Journal of Neurosurgery
|July 7, 2007
PubMed
Summary
This summary is machine-generated.

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Primary ventriculitis caused by Streptococcus intermedius, a rare central nervous system infection, can lead to severe complications. Early recognition and aggressive treatment are crucial for better patient outcomes.

Area of Science:

  • Neuroscience
  • Infectious Diseases
  • Microbiology

Background:

  • Streptococcus intermedius is an emerging cause of central nervous system infections.
  • Primary ventriculitis, an infection of the brain's ventricles, has not been previously reported with this pathogen.

Observation:

  • A case of primary ventriculitis caused by Streptococcus intermedius is presented.
  • The infection led to adhesions and multiloculated hydrocephalus, requiring multiple surgical interventions.
  • No predisposing factors were identified in the patient.

Findings:

  • Cultures of cerebrospinal fluid (CSF) were negative due to prior antibiotic treatment.
  • 16S rDNA polymerase chain reaction (PCR) successfully identified Streptococcus intermedius in the CSF sample.

Related Experiment Videos

  • This highlights the utility of molecular methods when traditional cultures fail.

    • Implications:

    • Early diagnosis and aggressive management of Streptococcus intermedius ventriculitis are essential.
    • Prompt treatment can prevent severe complications like adhesions and multiloculated hydrocephalus.
    • This case expands the known spectrum of central nervous system infections caused by Streptococcus intermedius.