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Burkitt lymphoma masquerading as cardiac tamponade
Pankaj Kaul1, Kalyana Javangula
1Department of Cardiothoracic Surgery, Yorkshire Heart Centre, Leeds General Infirmary, Great George Street, Leeds, LSI 3EX, UK. pankaj.kaul@leedsth.nhs.uk
Journal of Cardiothoracic Surgery
|July 7, 2007
Summary
This case report details a rare instance of Burkitt lymphoma presenting as cardiac tamponade. The patient developed three distinct lymphomas over eight years, highlighting atypical disease progression and presentation.
Area of Science:
- Oncology
- Hematology
- Pathology
Background:
- A 61-year-old male with a history of diffuse large B cell lymphoma and marginal zone lymphoma developed recurrent pericardial effusion.
- The patient presented with cardiac tamponade, a rare initial manifestation of lymphoma.
Observation:
- Surgical intervention revealed an enlarged paraaortic lymph node with histology confirming Burkitt lymphoma.
- This represents the third distinct lymphoma diagnosis in the patient over an eight-year period.
Findings:
- The Burkitt lymphoma exhibited an atypical, slow-growing phenotype with a high tumor doubling time.
- Chromosomal analysis was crucial in diagnosing this unusual presentation of Burkitt lymphoma.
Implications:
- This case underscores the importance of considering rare lymphoma presentations, such as cardiac tamponade.
- The occurrence of multiple distinct lymphomas in one patient raises questions about underlying mechanisms and potential transformations.
- Further research into the pathogenesis of sequential, distinct lymphomas and their cardiac involvement is warranted.
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