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Intracranial Implantation with Subsequent 3D In Vivo Bioluminescent Imaging of Murine Gliomas
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Published on: November 6, 2011

Multiple meningiomas in three dogs.

John J McDonnell1, Kerrianne Kalbko, John H Keating

  • 1Dogs and Cats Veterinary, Referral, Bowie, Maryland 20715, USA.

Journal of the American Animal Hospital Association
|July 7, 2007
PubMed
Summary

Three dogs experienced seizures due to multiple brain tumors called intracranial meningiomas. Treatments included surgery, radiation, or chemotherapy, with all dogs presenting two distinct tumors.

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Area of Science:

  • Veterinary Neurology
  • Canine Oncology
  • Neurosurgery

Background:

  • Intracranial meningiomas are common primary brain tumors in dogs.
  • Seizures are a frequent clinical sign associated with brain tumors.

Observation:

  • This study reports on three dogs diagnosed with multiple intracranial meningiomas.
  • The affected dogs were aged 9–11 years, with two being Golden Retrievers.
  • All cases presented with two distinct tumor masses identified via imaging, surgery, or necropsy.

Findings:

  • Treatment modalities included surgery and radiation (n=2) or chemotherapy (n=1).
  • Histological examination revealed two distinct meningiomas in all three dogs.
  • In two dogs, the meningiomas shared the same histological pattern; in one dog, different histological subtypes were observed.

Implications:

  • Multiple intracranial meningiomas can occur in dogs, presenting a complex diagnostic and therapeutic challenge.
  • Understanding the varied histological patterns is crucial for accurate diagnosis and treatment planning.
  • This case series highlights the importance of thorough diagnostic evaluation for canine brain tumors.